Re-infection Take 2

I want to quickly write a post on the recent case of re-infection coming out of the US. Specifically about the re-infection in a 25-yr old <2 months later, with worse symptoms second time around. Genetic discordance between the two infections was greater than explained by short-term in vivo evolution, ie, presumably two separate infections.

Transmission Risk as a Continuum

I’ve written before how risk of exposure to SARS-CoV-2 (the virus that causes Covid-19) is a continuum and that there are no exact risk thresholds for say duration of contact or appropriate distance. For instance, wearing a mask reduces risk but doesn’t eliminate it. It is the same with distancing. 6ft may not be sufficient

Unmasking the Mask Debate

I kid. In fact, this post will not be on whether masks are useful or not. Because we have ample evidence to show that masks, when used appropriately, reduces the transmission of SARS-CoV-2 (the virus that causes Covid-19). Instead, today I want to spend some time discussing what kinds of masks are effective, and what

94% 6% What did the CDC Say?

It’s been a few days since the CDC released data saying 94% of Covid-19 deaths had underlying medical conditions in addition to positive Covid-19 diagnosis. But I still see this misinformation being spread around — so I’d like to address this today. The way this has been interpreted is that the CDC “quietly updated” its COVID-19 data

Is a Positive Truly a Positive?

Today, a new article came out in 𝗡𝗬𝗧 on whether the 𝗖𝗼𝘃𝗶𝗱-𝟭𝟵 𝗣𝗖𝗥 𝘁𝗲𝘀𝘁 𝗶𝘀 𝘁𝗼𝗼 𝘀𝗲𝗻𝘀𝗶𝘁𝗶𝘃𝗲 𝗮𝗻𝗱 𝗶𝗳 𝘆𝗼𝘂𝗿 𝗽𝗼𝘀𝗶𝘁𝗶𝘃𝗲 𝘁𝗲𝘀𝘁 𝗶𝘀 𝗶𝗻𝗱𝗲𝗲𝗱 𝗮 𝗽𝗼𝘀𝗶𝘁𝗶𝘃𝗲 𝗼𝗿 𝗻𝗼𝘁. So let’s look into this a tad

Risk of SARS-CoV-2 Transmissions

This latest publication in BMJ, published 25 August 2020, by the University of Oxford has attempted to qualify the risk of SARS-CoV-2 transmission from asymptomatic people in different settings. This guide shows how transmission risk may vary with setting, occupancy level, contact time, and face coverings. This graph is intended to be an initial quick

Crash Course on Covd-19 Vaccines in Development

So, what’s the DL on Covid-19 Vaccines? Here’s a mini crash course for non-science folx. Given my education in clinical pharmacology and a fairly decent knowledge of cancer immunotherapies, I have been asked a lot of very good questions on the vaccines currently in development for Covid-19. There are so many vaccines currently in development,